VIP: How It Works, What It's Studied For & Safety
VIP is a 28-amino-acid neuropeptide with vasodilator, immunomodulatory, and circadian-signaling roles, studied in clinician-directed protocols for chronic inflammatory and post-viral indications. Clinicians consider it for chronic inflammatory response syndrome (CIRS) clinical-experience protocols. Not FDA-approved; dispensed by Wells Pharmacy Network only after a clinician evaluation.
Also known as: Vasoactive Intestinal Peptide
How does VIP work?
VIP is a member of the secretin/glucagon family. It binds VPAC1 and VPAC2 receptors on immune, endothelial, and CNS cells, modulating cytokine production, vasodilation, and suprachiasmatic-nucleus circadian signaling.
What is VIP studied for?
- Chronic inflammatory response syndrome (CIRS) clinical-experience protocols
- Post-viral fatigue and pulmonary research
- Circadian-rhythm research
How is VIP taken?
Compounded as a nasal spray in clinician-directed protocols.
Is VIP FDA-approved? Is it safe?
Not FDA-approved for the prevention, treatment, or cure of any condition. Used inside research-informed, clinician-directed protocols only. Compounded prescription-only preparations are dispensed by Wells Pharmacy Network. Eligibility is decided by a licensed clinician based on intake and labs, not by checkout. Compounded products on this site are not FDA-approved and are not generic equivalents of any branded medication.
In the Regen Therapy catalog
This compound does not currently appear in an active Regen Therapy protocol. Browse the full catalog for adjacent options.
What does the research say about VIP?
Mechanism is well-characterized in basic research; clinical use in CIRS-style protocols is clinical-experience-driven and lacks large randomized trials.
Citations & further reading
Considering VIP as part of a protocol?
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