Storage & Handling
  • Store unopened lyophilized vials at room temperature

  • After reconstitution: refrigerate at 36–46°F

  • Use within 24 hours

  • Single-use only; discard unused portion

  • Maintain strict aseptic technique  

Patient Eligibility & Safety
  • Review medical history, medications, allergies, and prior reactions

  • Avoid or use with caution in:

  • Active infection at injection site

  • Uncontrolled autoimmune disease

  • Active malignancy unless cleared

  • Pregnancy or breastfeeding (unless explicitly approved)

  • Obtain written informed consent including off-label disclosure

  • Record baseline vitals (HR, BP optional for SQ initiation)  


Preparation
  1. Reconstitution:

Reconstitute vial with 0.5-1mL sterile wateror sterile preferred normal saline

  • Inject slowly down vial wall

  • Gently swirl - do not shake

  • Ensure full dissolution before withdrawal  

2. Syringe Preparation

  • Use insulin syringe (29–31g, 0.3–1 mL)

  • Withdraw prescribed volume

  • Expel air bubbles carefully


Administration - Subcutaneous Injection

Injection Sites

  • Abdomen (≥2 inches from umbilicus)

  • Love handles / flank

  • Upper outer thigh

  • Rotate sites with each injection


Technique
  1. Clean site with alcohol prep

  2. Pinch subcutaneous tissue

  3. Insert needle at 45–90° angle

  4. Inject slowly over 5–10 seconds

  5. Withdraw needle, apply light pressure

  6. Do not massage aggressively


Adverse Event Management

Mild

  • Local erythema, swelling, itching

  • Cold compress, oral antihistamine if needed

  • Rotate injection sites

Moderate

  • Lightheadedness, flushing, nausea

  • Hold dose, hydrate, reassess dosing frequency

Severe (Rare)

  • Anaphylaxis, chest tightness, dyspnea

  • Activate emergency protocol

  • Administer epinephrine, oxygen, EMS per ACLS guidelines  


Regulatory Status
  • Quantum SQ administration is off-label

  • Intended for use only by licensed healthcare providers

  • Providers must be trained in injectable therapies and adverse-event management

  • Use within scope of state licensure and clinical practice guidelines