Humanin: How It Works, What It's Studied For & Safety
Humanin is a 24-amino-acid mitochondrial-derived peptide encoded within the 16S rRNA gene, studied for cytoprotective and metabolic-signaling effects. Clinicians consider it for neuroprotection research (Alzheimer's-related models). It is not FDA-approved as a finished drug product and is dispensed by Wells Pharmacy Network only after a licensed clinician evaluates intake, history, and labs.
Also known as: MOTS-c family, Mitochondrial-derived peptide
How does Humanin work?
Humanin is one of the first-discovered mitochondrial-derived peptides. Research describes anti-apoptotic signaling via interactions with Bax and other regulators, plus modulation of insulin sensitivity and neuronal survival pathways.
What is Humanin studied for?
- Neuroprotection research (Alzheimer's-related models)
- Insulin sensitivity and metabolic-aging research
- Cellular-stress and cytoprotection signaling
How is Humanin taken?
Compounded as a subcutaneous injection in clinician-directed cycles. Often paired with MOTS-c or SS-31 in mitochondrial-axis protocols.
Is Humanin FDA-approved? Is it safe?
Not FDA-approved for the prevention, treatment, or cure of any condition. Used inside research-informed, clinician-directed protocols only. Compounded prescription-only preparations are dispensed by Wells Pharmacy Network. Eligibility is decided by a licensed clinician based on intake and labs, not by checkout. Compounded products on this site are not FDA-approved and are not generic equivalents of any branded medication.
In the Regen Therapy catalog
This compound does not currently appear in an active Regen Therapy protocol. Browse the full catalog for adjacent options.
What does the research say about Humanin?
Foundational research from the Cohen lab at USC. Predominantly preclinical. No phase-2/3 clinical trial data.
Citations & further reading
Considering Humanin as part of a protocol?
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