Follistatin: How It Works, What It's Studied For & Safety
Follistatin is an endogenous glycoprotein that binds and neutralizes members of the TGF-β superfamily - including myostatin and activin - studied for muscle-mass and tissue-repair signaling. Clinicians consider it for muscle-mass and recovery research. Not FDA-approved; dispensed by Wells Pharmacy Network only after a clinician evaluation.
Also known as: FST, Follistatin-344, Follistatin-315
How does Follistatin work?
Follistatin sequesters myostatin (a negative regulator of skeletal-muscle mass) and activin A. Disinhibition of the muscle-growth pathway is studied for hypertrophy, recovery, and adjunctive support in muscle-wasting conditions.
What is Follistatin studied for?
- Muscle-mass and recovery research
- Preclinical models of sarcopenia and Duchenne muscular dystrophy
- Adjunct in clinician-directed body-composition protocols (investigational)
How is Follistatin taken?
Compounded as a subcutaneous injection in clinician-directed cycles. Recombinant and gene-therapy versions exist in academic research settings only.
Is Follistatin FDA-approved? Is it safe?
Not FDA-approved for the prevention, treatment, or cure of any condition. Used inside research-informed, clinician-directed protocols only. Human safety, dosing, and long-term effects are not established. Because follistatin engages broad TGF-β-family signaling, clinicians monitor for off-target effects. Compounded prescription-only preparations are dispensed by Wells Pharmacy Network. Eligibility is decided by a licensed clinician based on intake and labs, not by checkout. Compounded products on this site are not FDA-approved and are not generic equivalents of any branded medication.
In the Regen Therapy catalog
This compound does not currently appear in an active Regen Therapy protocol. Browse the full catalog for adjacent options.
What does the research say about Follistatin?
Strong preclinical literature on myostatin inhibition; small early-phase gene-therapy trials in muscular dystrophy. Compounded peptide preparations have no published controlled outcome trials.
Citations & further reading
Considering Follistatin as part of a protocol?
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