MOTS-c: How It Works, What It's Studied For & Safety
MOTS-c is a 16-amino-acid mitochondrial-derived peptide studied for its role in metabolic homeostasis, insulin sensitivity, and exercise capacity. Clinicians consider it for insulin sensitivity and metabolic-aging research. It is not FDA-approved as a finished drug product and is dispensed by Wells Pharmacy Network only after a licensed clinician evaluates intake, history, and labs.
Also known as: Mitochondrial open reading frame of the 12S rRNA-c
How does MOTS-c work?
MOTS-c is encoded within the mitochondrial 12S rRNA gene and is studied for activation of AMPK, modulation of glucose and fat metabolism, and skeletal-muscle exercise-response signaling.
What is MOTS-c studied for?
How is MOTS-c taken?
Compounded as a subcutaneous injection in clinician-directed cycles, often 2-3 times weekly.
Is MOTS-c FDA-approved? Is it safe?
Not FDA-approved for the prevention, treatment, or cure of any condition. Used inside research-informed, clinician-directed protocols only. Compounded prescription-only preparations are dispensed by Wells Pharmacy Network. Eligibility is decided by a licensed clinician based on intake and labs, not by checkout. Compounded products on this site are not FDA-approved and are not generic equivalents of any branded medication.
In the Regen Therapy catalog
The protocols below are dispensed by Wells Pharmacy Network and contain MOTS-c. Each one is prescribed only after a clinician evaluation.
What does the research say about MOTS-c?
A growing body of preclinical metabolic research; phase-1 work is in progress for related mitochondrial-axis compounds.
Citations & further reading
Considering MOTS-c as part of a protocol?
Browse Regen Therapy's catalog or start a clinician evaluation. Every prescription is reviewed by a licensed clinician and dispensed by Wells Pharmacy Network.
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