NAD+: How It Works, What It's Studied For & Safety
NAD+ is a coenzyme central to mitochondrial energy production and DNA-repair signaling whose tissue levels decline with age. Clinicians consider it for cellular-energy and healthy-aging research. It is not FDA-approved as a finished drug product and is dispensed by Wells Pharmacy Network only after a licensed clinician evaluates intake, history, and labs.
Also known as: Nicotinamide Adenine Dinucleotide
How does NAD+ work?
NAD+ is required for sirtuin and PARP enzyme activity, oxidative phosphorylation, and DNA-damage response signaling. Direct administration aims to raise tissue pools that decline with age, oxidative stress, and certain disease states.
What is NAD+ studied for?
- Cellular-energy and healthy-aging research
- Adjunct in post-viral and recovery protocols
- Cognitive support in clinician-directed cycles
How is NAD+ taken?
Compounded as a subcutaneous injection (cycled blocks) and as a nasal spray (between cycles or as a daily option). IV preparations are administered in clinic.
Is NAD+ FDA-approved? Is it safe?
Not FDA-approved for the prevention, treatment, or cure of any condition. Used inside research-informed, clinician-directed protocols only. Reported research effects during infusion include nausea, flushing, and chest tightness - slow administration is standard. Compounded prescription-only preparations are dispensed by Wells Pharmacy Network. Eligibility is decided by a licensed clinician based on intake and labs, not by checkout. Compounded products on this site are not FDA-approved and are not generic equivalents of any branded medication.
In the Regen Therapy catalog
This compound does not currently appear in an active Regen Therapy protocol. Browse the full catalog for adjacent options.
What does the research say about NAD+?
Mechanistic biology is well-characterized; clinical efficacy data for NAD+ direct administration in healthy aging is still emerging.
Citations & further reading
Considering NAD+ as part of a protocol?
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