Selank: How It Works, What It's Studied For & Safety
Selank is a synthetic heptapeptide analog of the endogenous immunomodulator tuftsin, originally developed in Russia and studied for anxiolytic and cognitive-modulation effects. Clinicians consider it for generalized-anxiety and stress-resilience research (Russian clinical studies). Not FDA-approved; dispensed by Wells Pharmacy Network only after a clinician evaluation.
Also known as: Threonyl-lysyl-prolyl-arginyl-prolyl-glycyl-proline, TKPRPGP
How does Selank work?
Selank is a stable, blood-brain-barrier-penetrating analog of tuftsin (a tetrapeptide derived from immunoglobulin Fc). It is studied for modulation of GABAergic and serotonergic signaling, BDNF expression, and immune cytokine balance, with preclinical anxiolytic effects without sedation or dependence liability.
What is Selank studied for?
- Generalized-anxiety and stress-resilience research (Russian clinical studies)
- Cognitive-modulation and attention research
- Adjunct in clinician-directed mood and post-burnout protocols (off-label, investigational)
How is Selank taken?
Compounded as an intranasal spray (most common route) or subcutaneous injection in clinician-directed protocols. Not FDA-approved.
Is Selank FDA-approved? Is it safe?
Not FDA-approved for the prevention, treatment, or cure of any condition. Used inside research-informed, clinician-directed protocols only. Reported research safety has been favorable, with no observed sedation or dependence in published Russian studies. Long-term human safety data outside that literature is limited. Compounded prescription-only preparations are dispensed by Wells Pharmacy Network. Eligibility is decided by a licensed clinician based on intake and labs, not by checkout. Compounded products on this site are not FDA-approved and are not generic equivalents of any branded medication.
In the Regen Therapy catalog
This compound does not currently appear in an active Regen Therapy protocol. Browse the full catalog for adjacent options.
What does the research say about Selank?
Russian clinical literature reports anxiolytic effects in generalized anxiety disorder; Western controlled trials are not available.
Citations & further reading
Considering Selank as part of a protocol?
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