SLU-PP-332: How It Works, What It's Studied For & Safety
SLU-PP-332 is a small-molecule pan-agonist of estrogen-related receptors (ERRα, β, γ) studied as an exercise mimetic for endurance, fat oxidation, and mitochondrial biogenesis in preclinical models. Clinicians consider it for preclinical endurance and fat-oxidation research (exercise-mimetic). Not FDA-approved; dispensed by Wells Pharmacy Network only after a clinician evaluation.
Also known as: ERR pan-agonist
How does SLU-PP-332 work?
SLU-PP-332 activates the ERR family of orphan nuclear receptors, master regulators of mitochondrial biogenesis and oxidative metabolism. In preclinical models it shifts skeletal-muscle gene expression toward type-1 oxidative fibers, increases endurance, and improves fat oxidation without requiring exercise itself.
What is SLU-PP-332 studied for?
- Preclinical endurance and fat-oxidation research (exercise-mimetic)
- Mitochondrial-biogenesis research
- Adjunct in clinician-directed metabolic and body-composition protocols (investigational)
How is SLU-PP-332 taken?
Compounded oral preparations in clinician-directed protocols. Not FDA-approved and not commercially available as a finished drug product.
Is SLU-PP-332 FDA-approved? Is it safe?
Not FDA-approved for the prevention, treatment, or cure of any condition. Used inside research-informed, clinician-directed protocols only. Human safety, dosing, and long-term effects are not established. ERR signaling is broad, so clinician oversight and lab monitoring are appropriate. Compounded prescription-only preparations are dispensed by Wells Pharmacy Network. Eligibility is decided by a licensed clinician based on intake and labs, not by checkout. Compounded products on this site are not FDA-approved and are not generic equivalents of any branded medication.
In the Regen Therapy catalog
This compound does not currently appear in an active Regen Therapy protocol. Browse the full catalog for adjacent options.
What does the research say about SLU-PP-332?
Mouse studies report increased running endurance, improved fat oxidation, and mitochondrial-biogenesis gene-expression changes. No published controlled human trials.
Citations & further reading
Considering SLU-PP-332 as part of a protocol?
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