Tesamorelin: How It Works, What It's Studied For & Safety
Tesamorelin is a stabilized GHRH analog FDA-approved for HIV-associated lipodystrophy and studied for visceral-fat reduction in adults. Clinicians consider it for visceral adipose tissue (VAT) reduction in HIV-associated lipodystrophy (FDA-approved indication). Branded products are FDA-approved under labeled indications; compounded variants are dispensed by Wells Pharmacy Network only after a licensed clinician evaluates intake, history, and labs.
Also known as: Egrifta, TH9507
How does Tesamorelin work?
Tesamorelin is a synthetic 44-amino-acid GHRH analog designed for resistance to enzymatic breakdown. It stimulates the pituitary's release of endogenous growth hormone, producing dose-dependent reductions in visceral adipose tissue in studied populations.
What is Tesamorelin studied for?
- Visceral adipose tissue (VAT) reduction in HIV-associated lipodystrophy (FDA-approved indication)
- Off-label adult VAT reduction in clinician-directed body-composition protocols
- Cognitive research in adults with HIV-related neurocognitive concerns
How is Tesamorelin taken?
FDA-approved as a daily subcutaneous injection (Egrifta). Compounded preparations exist for off-label clinician-directed protocols.
Is Tesamorelin FDA-approved? Is it safe?
FDA-approved as a finished drug product when prescribed under its labeled indications. Compounded variants on this site are separate from the branded product and are dispensed only when a clinician determines a compounded preparation is appropriate. Compounded prescription-only preparations are dispensed by Wells Pharmacy Network. Eligibility is decided by a licensed clinician based on intake and labs, not by checkout. Compounded products on this site are not FDA-approved and are not generic equivalents of any branded medication.
In the Regen Therapy catalog
The protocols below are dispensed by Wells Pharmacy Network and contain Tesamorelin. Each one is prescribed only after a clinician evaluation.
What does the research say about Tesamorelin?
Phase-3 trials demonstrated significant VAT reduction in HIV-lipodystrophy patients; off-label use in healthy adults is clinical-experience-driven.
Citations & further reading
Considering Tesamorelin as part of a protocol?
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